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HEPACAM2 (基因名), HEPACAM family member 2 (蛋白名), heca2_human.
产品名称:

Human HEPACAM2/ HEPACAM family member 2 Recombinant Protein

货号:

R16162h

商标:
EIAab®
监管等级:
别名:

Mitotic kinetics regulator, UNQ305/PRO346, MIKI

序列号:
A8MVW5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human HEPACAM2 Protein
规格 & 价格: cart
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Human HEPACAM2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7q21.2 by HGNC 7q21.2 by Entrez Gene 7q21.2 by Ensembl
HEPACAM2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Required during prometaphase for centrosome maturation. Following poly-ADP-ribosylation (PARsylation) by TNKS, translocates from the Golgi apparatus to mitotic centrosomes and plays a key role in the formation of robust microtubules for prompt movement of chromosomes: anchors AKAP9/CG-NAP, a scaffold protein of the gamma-tubulin ring complex and promotes centrosome maturation.


亚细胞位置:
Golgi apparatus membrane Single-pass type I membrane protein Cytoplasm Cytoskeleton Spindle Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Midbody In interphase, localizes to the Golgi apparatus. Localizes to centrosomes and spindles during prophase, prometaphase, and metaphase of mitosis, and to midbodies at telophase. Translocation to mitotic centrosomes is the result of poly-ADP-ribosylation (PARsylation).


该产品尚未在任何出版物中被引用。

[1].
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."

[2].
"Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation."

[3].
"Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"Architecture of the human interactome defines protein communities and disease networks."

[6].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[7].
"Effects of smoking cessation on gene expression in human leukocytes of chronic smoker."

[8].
"Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium."

[9].
"Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma."

[10].
"Myoclonus dystonia plus syndrome due to a novel 7q21 microdeletion."
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