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HTN3 (基因名), Histatin-3 (蛋白名), his3_human.
产品名称:

Human HTN3/ Histatin-3 Recombinant Protein
富组蛋白

货号:

R1516h

商标:
EIAab®
监管等级:
别名:

Basic histidine-rich protein, Histidine-rich protein 3, PB, Hst, HIS2

序列号:
P15516
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Metabolism
Human HTN3 Protein
规格 & 价格: cart
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Human HTN3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q13.3 by HGNC 4q13.3 by Entrez Gene 4q13.3 by Ensembl
HTN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
His3-(20-43)-peptide is a homodimer. Histatin-3 and His3-(20-43)-peptide interact with yeast SSA1 and SSA2 proteins.


功能:
Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9.


亚细胞位置:
Secreted Secreted by serous acinar and demilune cells.


该产品尚未在任何出版物中被引用。

[1].
"Polymorphism of salivary histatin gene and periodontal disease in the Japanese population."

[2].
"A cascade of 24 histatins (histatin 3 fragments) in human saliva. Suggestions for a pre-secretory sequential cleavage pathway."

[3].
"Zinc and copper bind to unique sites of histatin 5."

[4].
"Candidacidal activity of recombinant human salivary histatin-5 and variants."

[5].
"Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family."

[6].
"Molecular cloning of human submandibular histatins."

[7].
"Cooperation of salivary protein histatin 3 with heat shock cognate protein 70 relative to the G1/S transition in human gingival fibroblasts."

[8].
"Human antimicrobial peptide histatin 5 is a cell-penetrating peptide targeting mitochondrial ATP synthesis in Leishmania."

[9].
"Metal-binding and nuclease activity of an antimicrobial peptide analogue of the salivary histatin 5."

[10].
"Immunocytochemical localization of histatins in human salivary glands."
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