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HMMR (基因名), Hyaluronan mediated motility receptor (蛋白名), hmmr_human.
产品名称:

Human HMMR/ Hyaluronan mediated motility receptor Recombinant Protein
透明质酸介导运动因子受体

货号:

R9486h

商标:
EIAab®
监管等级:
别名:

Intracellular hyaluronic acid-binding protein, Receptor for hyaluronan-mediated motility, CD168, IHABP, RHAMM

序列号:
O75330
来源:
E.coli
种属:
Human
标签:
His
序列:
180-312aa
预估分子量:
14.63 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human HMMR Protein
  • Human HMMR Protein
  • Human HMMR Protein
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Human HMMR Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human HMMR Protein
The PCR product of human HMMR gene was determined by 1% Agarose stained with EB.
Human HMMR Protein
Recombinant human HMMR protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 5q34 by HGNC 5q34 by Entrez Gene 5q34 by Ensembl
HMMR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Subunit of the HARC complex. Interacts with ANKRD26 (PubMed:22666460).


功能:
Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).


亚细胞位置:
Cell surface Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Hyaluronan-mediated motility receptor gene single nucleotide polymorphisms and risk of breast cancer."

[2].
"The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells."

[3].
"ANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cells."

[4].
"Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas."

[5].
"RHAMM (CD168) is overexpressed at the protein level and may constitute an immunogenic antigen in advanced prostate cancer disease."

[6].
"Acute lymphoblastic leukemia-derived dendritic cells express tumor associated antigens: PNPT1, PMPCB, RHAMM, BSG and ERCC1."

[7].
"The tumor antigens RHAMM and G250/CAIX are expressed in head and neck squamous cell carcinomas and elicit specific CD8+ T cell responses."

[8].
"The candidate immunotherapeutical target, the receptor for hyaluronic acid-mediated motility, is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia."

[9].
"Filling the mosaic of p53 actions: p53 represses RHAMM expression."

[10].
"RHAMM, p21 combined phenotype identifies microsatellite instability-high colorectal cancers with a highly adverse prognosis."
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