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Homer2 (基因名), Homer protein homolog 2 (蛋白名), home2_mouse.
产品名称:

Mouse Homer2/ Homer protein homolog 2 Recombinant Protein

货号:

R2788m

商标:
EIAab®
监管等级:
别名:

Cupidin, VASP/Ena-related gene up-regulated during seizure and LTP 2, Vesl-2, Homer-2, Vesl2

序列号:
Q9QWW1
来源:
E.coli
种属:
Mouse
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Mouse Homer2 Protein
规格 & 价格: cart
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Mouse Homer2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Forms coiled-coil structures coiled-coil structures that mediate homo- and heteromultimerization.


功能:
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2 (By similarity). Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (By similarity) Required for normal hearing (PubMed:25816005).


亚细胞位置:
Cytoplasm Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell junction Synapse Cell projection Stereocilium Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.


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