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HPGDS (基因名), Hematopoietic prostaglandin D synthase (蛋白名), hpgds_human.
产品名称:

Human HPGDS/ Hematopoietic prostaglandin D synthase Recombinant Protein
造血前列腺素D合成

货号:

R15054h

商标:
EIAab®
监管等级:
别名:

GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomerase, H-PGDS, GSTS, PGDS, PTGDS2

序列号:
O60760
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human HPGDS Protein
规格 & 价格: cart
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Human HPGDS Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 4q22.3 by HGNC 4q22.3 by Entrez Gene 4q22.3 by Ensembl
HPGDS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.


亚细胞位置:
Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases."

[2].
"Novel prostaglandin D synthase inhibitors generated by fragment-based drug design."

[3].
"First determination of the inhibitor complex structure of human hematopoietic prostaglandin D synthase."

[4].
"Structure and chromosomal localization of human and mouse genes for hematopoietic prostaglandin D synthase. Conservation of the ancestral genomic structure of sigma-class glutathione S-transferase."

[5].
"Prostaglandin D synthase in human megakaryoblastic cells."

[6].
"Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase."

[7].
"Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"Mechanism of metal activation of human hematopoietic prostaglandin D synthase."

[10].
"Induction of hematopoietic prostaglandin D synthase in human megakaryocytic cells by phorbol ester."
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