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HYAL1 (基因名), Hyaluronidase-1 (蛋白名), hyal1_human.
产品名称:

Human HYAL1/ Hyaluronidase-1 Recombinant Protein
透明质酸酶-1

货号:

R1217h

商标:
EIAab®
监管等级:
别名:

Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, Hyal-1, LUCA1

序列号:
Q12794
来源:
E.coli
种属:
Human
标签:
His
序列:
183-435aa
预估分子量:
27.83 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
  • Human HYAL1 Protein
  • Human HYAL1 Protein
  • Human HYAL1 Protein
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Human HYAL1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human HYAL1 Protein
The PCR product of human HYAL1 gene was determined by 1% Agarose stained with EB.
Human HYAL1 Protein
Recombinant human HYAL1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p21.31 by HGNC 3p21.31 by Entrez Gene 3p21.31 by Ensembl
HYAL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.


亚细胞位置:
Secreted Lysosome


该产品尚未在任何出版物中被引用。

[1].
"Purification, cloning, and expression of human plasma hyaluronidase."

[2].
"Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis."

[3].
"Regulation of hyaluronidase activity by alternative mRNA splicing."

[4].
"HYAL1LUCA-1, a candidate tumor suppressor gene on chromosome 3p21.3, is inactivated in head and neck squamous cell carcinomas by aberrant splicing of pre-mRNA."

[5].
"Mutations in HYAL1, a member of a tandemly distributed multigene family encoding disparate hyaluronidase activities, cause a newly described lysosomal disorder, mucopolysaccharidosis IX."

[6].
"Purification and microsequencing of hyaluronidase isozymes from human urine."

[7].
"Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia."

[8].
"Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content."

[9].
"Designed human serum hyaluronidase 1 variant, HYAL1DeltaL, exhibits activity up to pH 5.9."

[10].
"[Down-regulation of RBSP3/CTDSPL, NPRL2/G21, RASSF1A, ITGA9, HYAL1 and HYAL2 genes in non-small cell lung cancer]."
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