首页 > 重组蛋白 > Human IL17A Recombinant Protein

IL17A (基因名), Interleukin-17A (蛋白名), il17_human.

产品名称:

Human IL17A/ Interleukin-17A Recombinant Protein
白介素17A

货号:

R0063h

商标:

EIAab^®

监管等级:

RUO

别名:

Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL-17, CTLA8, IL17

序列号:

Q16552

来源:

E.coli

种属:

Human

标签:

His

序列:

21-190aa

预估分子量:

18.7 kDa (monomer)

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Immunology

规格 & 价格:

关注

Human IL17A Protein

邮箱 *

消息 *

Please 登录.

产品说明书

说明书:

MSDS:

在线询价

数据
文献 ( 6 )
出版物
序列 / 3D
视频
常见问题解答
反馈墙 (0)

R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 6p12.2 by HGNC 6p12.2 by Entrez Gene 6p12.2 by Ensembl

IL17A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Homodimer (PubMed:19835883). Heterodimer with IL17F (PubMed:17355969).

功能:

Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).

亚细胞位置:

Secreted

数据库链接

UniGene:

Hs.41724

SMR:

Q16552

STRING:

9606.ENSP00000344192

KEGG:

hsa:3605

MIM:

603149

Pfam:

PF06083

Uniprot:

Q16552

相关产品

Mouse Il17a ELISA Kit

Rat Il17a ELISA Kit

Bovine IL17A ELISA Kit

Pig IL17A ELISA Kit

Mouse Il17a CLIA Kit

序列长度:

155

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

157:

PIVHHVA

3D 模型:

3D 结构:

免疫原序列:

验证序列:

[1].

"Role of YAP-related T cell imbalance and epidermal keratinocyte dysfunction in the pathogenesis of atopic dermatitis"

Jj Jia, Xm Mo, Fg Yan, et al.

From: Journal of Dermatological Science

[2].

"Serum and ascitic fluid interleukin-17 in spontaneous bacterial peritonitis in Egyptian patients with HCV-related liver cirrhosis"

A A Mohammed, A M Higazi, Z M Saad, et al.

From: Current Research in Translational Medicine

[3].

"Plasma Levels of IL-17, VEGF, and Adrenomedullin and S-Cone Dysfunction of the Retina in Children and Adolescents without Signs of Retinopathy ..."

K Semeran, P Pawłowski, L Lisowski, et al.

From: Mediators of Inflammation

[4].

"Expression levels of IL-27 and IL-17 in multiple myeloma patients: A higher ratio of IL-27:IL-17 in bone marrow was associated with a superior..."

XN Song, JZ Yang, LX Sun, et al.

From: Leukemia Research

[5].

"Plasma Levels of IL-23 and IL-17 before and after Antidepressant Treatment in Patients with Major Depressive Disorder"

JW Kim, YK Kim, JA Hwang, et al.

From: psychiatry investigation

[6].

"Interleukin-17 receptor expression on vascular endothelial cells of masses of skeletal extramedullary disease in myeloma patients"

JZ Yang, Y Li, LX Sun, et al.

From: Pathology-Research and Practice

[1].

"Structure of IL-17A in complex with a potent, fully human neutralizing antibody."

(PMID: 19835883)

[2].

"Interleukin-17A gene variants and risk of coronary artery disease: a large angiography-based study."

(PMID: 21062626)

[3].

"A role for IL-17 in induction of an inflammation at the fetomaternal interface in preterm labour."

(PMID: 19969371)

[4].

"IL-17 contributes to angiogenesis in rheumatoid arthritis."

(PMID: 20173024)

[5].

"Differential IL-17 production and mannan recognition contribute to fungal pathogenicity and commensalism."

(PMID: 20228201)

[6].

"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

(PMID: 20379614)

[7].

"Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer."

(PMID: 20418110)

[8].

"Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls."

(PMID: 20503287)

[9].

"The role of T-helper 17 (Th17) cells in patients with medulloblastoma."

(PMID: 20515574)

[10].

"IL-17 in cutaneous lupus erythematosus."

(PMID: 20493423)

[1].

人白介素17A(IL17A)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人白介素17A(IL17A)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人白介素17A(IL17A)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人白介素17A(IL17A)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人白介素17A(IL17A)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人白介素17A(IL17A)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人白介素17A(IL17A)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人白介素17A(IL17A)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

更多 >

反馈墙

评论数 : 0

所有用户

默认排序

Human IL17A/ Interleukin-17A Recombinant Protein白介素17A

R0063h

Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, IL-17, CTLA8, IL17

Human IL17A/ Interleukin-17A Recombinant Protein
白介素17A