EIAab
首页  >  重组蛋白  >  Human KCNJ12 Recombinant Protein
KCNJ12 (基因名), ATP-sensitive inward rectifier potassium channel 12 (蛋白名), irk12_human.
产品名称:

Human KCNJ12/ ATP-sensitive inward rectifier potassium channel 12 Recombinant Protein

货号:

R5743h

商标:
EIAab®
监管等级:
别名:

Inward rectifier K(+) channel Kir2.2, Inward rectifier K(+) channel Kir2.2v, Potassium channel, inwardly rectifying subfamily J member 12, IRK-2, IRK2, KCNJN1

序列号:
Q14500
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human KCNJ12 Protein
规格 & 价格: cart
×
Human KCNJ12 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17p11.2 by HGNC 17p11.2 by Entrez Gene 17p11.2 by Ensembl
KCNJ12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Association, via its PDZ-recognition domain, with LIN7A, LIN7B, LIN7C, DLG1, CASK and APBA1 plays a key role in its localization and trafficking.


功能:
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.


亚细胞位置:
Membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Identification of human Kir2.2 (KCNJ12) gene encoding functional inward rectifier potassium channel in both mammalian cells and Xenopus oocytes."

[2].
"Cloning and functional expression of an inwardly rectifying K+ channel from human atrium."

[3].
"Hundreds of variants clustered in genomic loci and biological pathways affect human height."

[4].
"Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate."

[5].
"Regulation of cardiac inwardly rectifying potassium current IK1 and Kir2.x channels by endothelin-1."

[6].
"International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels."

[7].
"Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery."

[10].
"Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com