EIAab
首页  >  重组蛋白  >  Human JADE2 Recombinant Protein
JADE2 (基因名), E3 ubiquitin-protein ligase Jade-2 (蛋白名), jade2_human.
产品名称:

Human JADE2/ E3 ubiquitin-protein ligase Jade-2 Recombinant Protein

货号:
-
商标:
EIAab®
监管等级:
别名:

Jade family PHD finger protein 2, PHD finger protein 15, KIAA0239, PHF15

序列号:
Q9NQC1
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human JADE2 Protein
×
Human JADE2 Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


基因位点
Cytogenetic band: 5q31.1 by HGNC 5q31.1 by Entrez Gene 5q31.1 by Ensembl
JADE2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of JADE1, JADE2 and JADE3 (PubMed:16387653). Interacts (via C-terminus) with KDM1A (via AOD/Tower domain) (PubMed:25018020).


功能:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis (By similarity).


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation."

[2].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[3].
"Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones."

[4].
"Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development."

[5].
"Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing."

[8].
"Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease."

[9].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[10].
"A human interactome in three quantitative dimensions organized by stoichiometries and abundances."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com