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首页  >  重组蛋白  >  Human SPAG9 Recombinant Protein
SPAG9 (基因名), C-Jun-amino-terminal kinase-interacting protein 4 (蛋白名), jip4_human.
产品名称:

Human SPAG9/ C-Jun-amino-terminal kinase-interacting protein 4 Recombinant Protein
C-Jun氨基末端激酶相互作用蛋白4

货号:

R12202h

商标:
EIAab®
监管等级:
别名:

Cancer/testis antigen 89, Sunday driver 1, Human lung cancer oncogene 6 protein, JNK-associated leucine-zipper protein, Mitogen-activated protein kinase 8-interacting protein 4, Proliferation-inducing protein 6, Protein highly expressed in testis, Sperm surface protein, Sperm-associated antigen 9, Sperm-specific protein, CT89, HLC-6, JLP, PHET, HLC6, JIP-4, HSS, KIAA0516, MAPK8IP4, SYD1

序列号:
O60271
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human SPAG9 Protein
规格 & 价格: cart
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Human SPAG9 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 17q21.33 by HGNC 17q21.33 by Entrez Gene 17q21.33 by Ensembl
SPAG9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. The homodimer interacts with ARF6, forming a heterotetramer. Homooligomer. Interacts with MAX, MAPK8, MAPK9, MAPK10, MAPK14, MAP3K3, MYC, KNS2 and MAP2K4. Interaction with KNS2 is important in the formation of ternary complex with MAPK8. Interacts with NFKB1.


功能:
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg-interaction.


亚细胞位置:
Isoform 5 Cytoplasmic vesicle Secretory vesicle Acrosome Associated with the plasma membrane of the acrosomal compartment and also localizes in the acrosome matrix.


该产品尚未在任何出版物中被引用。

[1].
"Cloning of a novel human testis mRNA specifically expressed in testicular haploid germ cells, having unique palindromic sequences and encoding a leucine zipper dimerization motif."

[2].
"Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein."

[3].
"A novel protein highly expressed in testis is overexpressed in systemic sclerosis fibroblasts and targeted by autoantibodies."

[4].
"JLP: A scaffolding protein that tethers JNK/p38MAPK signaling modules and transcription factors."

[5].
"Sperm associated antigen 9 expression and humoral response in chronic myeloid leukemia."
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