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KIF22 (基因名), Kinesin-like protein KIF22 (蛋白名), kif22_human.
产品名称:

Human KIF22/ Kinesin-like protein KIF22 Recombinant Protein

货号:

R11898h

商标:
EIAab®
监管等级:
别名:

Kinesin-like DNA-binding protein, Kinesin-like protein 4, KID, KNSL4

序列号:
Q14807
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human KIF22 Protein
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Human KIF22 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 16p11.2 by HGNC 16p11.2 by Entrez Gene 16p11.2 by Ensembl
KIF22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with FAM83D (PubMed:18485706). Interacts with SIAH1 (PubMed:11146551).


功能:
Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205).


亚细胞位置:
Nucleus Cytoplasm Cytoskeleton


该产品尚未在任何出版物中被引用。

[1].
"Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle."

[2].
"SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis."

[3].
"Human genes for KNSL4 and MAZ are located close to one another on chromosome 16p11.2."

[4].
"Chromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubules."

[5].
"Whole-exome sequencing identifies mutations of KIF22 in spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type."

[6].
"Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity."

[7].
"Distinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes."

[8].
"The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"The human chromokinesin Kid is a plus end-directed microtubule-based motor."
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