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KIF4A (基因名), Chromosome-associated kinesin KIF4A (蛋白名), kif4a_human.
产品名称:

Human KIF4A/ Chromosome-associated kinesin KIF4A Recombinant Protein

货号:

R11880h

商标:
EIAab®
监管等级:
别名:

Chromokinesin-A, KIF4

序列号:
O95239
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human KIF4A Protein
规格 & 价格: cart
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Human KIF4A Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xq13.1 by HGNC Xq13.1 by Entrez Gene Xq13.1 by Ensembl
KIF4A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with unphosphorylated PRC1 during late mitosis.


功能:
Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.


亚细胞位置:
Nucleus matrix Cytoplasm Cytoskeleton Spindle Midbody Chromosome Not present in the nucleolus. In early mitosis, associated with the mitotic spindle, in anaphase, localized to the spindle midzone and, in telophase and cytokinesis, to the midbody. In late cytokinesis, found in the center of the midbody. Associated with chromosomes at all stages of mitosis.


该产品尚未在任何出版物中被引用。

[1].
"Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis."

[2].
"Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation."

[3].
"Human kinesin superfamily member 4 is dominantly localized in the nuclear matrix and is associated with chromosomes during mitosis."

[4].
"Increased chromokinesin immunoreactivity in retinoblastoma cells."

[5].
"Structural requirements of chromokinesin Kif4A for its proper function in mitosis."

[6].
"KIF14 and citron kinase act together to promote efficient cytokinesis."

[7].
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."

[8].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[9].
"The DNA sequence of the human X chromosome."

[10].
"Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference."
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