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LAMB3 (基因名), Laminin subunit beta-3 (蛋白名), lamb3_human.
产品名称:

Human LAMB3/ Laminin subunit beta-3 Recombinant Protein
层粘连蛋白亚基β3

货号:

R1471h

商标:
EIAab®
监管等级:
别名:

Epiligrin subunit bata, Kalinin B1 chain, Kalinin subunit beta, Laminin B1k chain, Laminin-5 subunit beta, Nicein subunit beta, LAMNB1

序列号:
Q13751
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human LAMB3 Protein
规格 & 价格: cart
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Human LAMB3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1q32.2 by HGNC 1q32.2 by Entrez Gene 1q32.2 by Ensembl
LAMB3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-3 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein). Interacts with ECM1.


功能:
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.


亚细胞位置:
Secreted Extracellular space Extracellular matrix Basement membrane


该产品尚未在任何出版物中被引用。

[1].
"Cloning of the beta 3 chain gene (LAMB3) of human laminin 5, a candidate gene in junctional epidermolysis bullosa."

[2].
"Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women."

[3].
"Revertant mosaicism in junctional epidermolysis bullosa due to multiple correcting second-site mutations in LAMB3."

[4].
"Evaluation of the ARMD1 locus on 1q25-31 in patients with age-related maculopathy: genetic variation in laminin genes and in exon 104 of HEMICENTIN-1."

[5].
"In vivo restoration of laminin 5 beta 3 expression and function in junctional epidermolysis bullosa."

[6].
"E210K mutation in the gene encoding the beta3 chain of laminin-5 (LAMB3) is predictive of a phenotype of generalized atrophic benign epidermolysis bullosa."

[7].
"Detection of sequence variants in the gene encoding the beta 3 chain of laminin 5 (LAMB3)."

[8].
"The complete primary structure for a novel laminin chain, the laminin B1k chain."

[9].
"Whole-exome sequencing, without prior linkage, identifies a mutation in LAMB3 as a cause of dominant hypoplastic amelogenesis imperfecta."

[10].
"LAMB3 mutations causing autosomal-dominant amelogenesis imperfecta."
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