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LARP6 (基因名), La-related protein 6 (蛋白名), larp6_human.
产品名称:

Human LARP6/ La-related protein 6 Recombinant Protein

货号:

R14791h

商标:
EIAab®
监管等级:
别名:

Acheron, La ribonucleoprotein domain family member 6, Achn

序列号:
Q9BRS8
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human LARP6 Protein
规格 & 价格: cart
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Human LARP6 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 15q23 by HGNC 15q23 by Entrez Gene 15q23 by Ensembl
LARP6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts (via the HTH domain) with VIM/vimentin. Interacts (via C-terminus) with non-muscle myosin MYH10. Interacts (via C-terminus) with DHX9.


功能:
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.


亚细胞位置:
Cytoplasm Nucleus Shuttles between the nucleus and the cytoplasm.


该产品尚未在任何出版物中被引用。

[1].
"A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs."

[2].
"A novel role of vimentin filaments: binding and stabilization of collagen mRNAs."

[3].
"Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen."

[4].
"Nonmuscle myosin-dependent synthesis of type I collagen."

[5].
"Acheron, a novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."

[9].
"Architecture of the human interactome defines protein communities and disease networks."

[10].
"The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives."
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