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首页  >  重组蛋白  >  Human LCN1 Recombinant Protein
LCN1 (基因名), Lipocalin-1 (蛋白名), lcn1_human.
产品名称:

Human LCN1/ Lipocalin-1 Recombinant Protein
脂质运载蛋白1

货号:

R1413h

商标:
EIAab®
监管等级:
别名:

Tear lipocalin, Tear prealbumin, Von Ebner gland protein, Tlc, TP, VEG protein, VEGP

序列号:
P31025
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human LCN1 Protein
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Human LCN1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q34.3 by HGNC 9q34.3 by Entrez Gene 9q34.3 by Ensembl
LCN1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer (By similarity). Binds to LMBR1L which may mediate its endocytosis.


功能:
Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.


亚细胞位置:
Secreted



[1].
"The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands."

[2].
"Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells."

[3].
"Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display."

[4].
"Structural organization of the gene encoding the human lipocalin tear prealbumin and synthesis of the recombinant protein in Escherichia coli."

[5].
"Assignment of the human tear lipocalin gene (LCN1) to 9q34 by in situ hybridization."

[6].
"Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands."

[7].
"cDNA cloning and sequencing reveals human tear prealbumin to be a member of the lipophilic-ligand carrier protein superfamily."

[8].
"A new crystal form of human tear lipocalin reveals high flexibility in the loop region and induced fit in the ligand cavity."

[9].
"Oligomeric state of lipocalin-1 (LCN1) by multiangle laser light scattering and fluorescence anisotropy decay."

[10].
"Evidence for internal and external binding sites on human tear lipocalin."
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