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LGALS3BP (基因名), Galectin-3-binding protein (蛋白名), lg3bp_human.
产品名称:

Human LGALS3BP/ Galectin-3-binding protein Recombinant Protein
galectin-3-binding蛋白

货号:

R15091h

商标:
EIAab®
监管等级:
别名:

Basement membrane autoantigen p105, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, Tumor-associated antigen 90K, MAC2BP, M2BP

序列号:
Q08380
来源:
E.coli
种属:
Human
标签:
His
序列:
114-232aa
预估分子量:
13.09 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
  • Human LGALS3BP Protein
  • Human LGALS3BP Protein
  • Human LGALS3BP Protein
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Human LGALS3BP Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human LGALS3BP Protein
The PCR product of human LGALS3BP gene was determined by 1% Agarose stained with EB.
Human LGALS3BP Protein
Recombinant human LGALS3BP protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 17q25 by HGNC 17q25 by Entrez Gene 17q25 by Ensembl
LGALS3BP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimers and homomultimers. The multimers form ring-like structures with a diameter of 30-40 nm. Binds LGALS1 and LGALS3. Binds ITGB1, COL4A1, COL5A1, COL6A1, FN1 and NID.


功能:
Promotes intergrin-mediated cell adhesion. May stimulate host defense against viruses and tumor cells.


亚细胞位置:
Secreted Secreted Extracellular space Extracellular matrix


该产品尚未在任何出版物中被引用。

[1].
"The secreted tumor-associated antigen 90K is a potent immune stimulator."

[2].
"Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain."

[3].
"Functional studies on recombinant domains of Mac-2-binding protein."

[4].
"Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation."

[5].
"Mac-2 binding protein is a cell-adhesive protein of the extracellular matrix which self-assembles into ring-like structures and binds beta1 integrins, collagens and fibronectin."

[6].
"The gene (LGALS3BP) encoding the serum protein 90K, associated with cancer and infection by the human immunodeficiency virus, maps at 17q25."

[7].
"EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions."

[8].
"Identification of Mac-2-binding protein as a putative marker of neuroendocrine tumors from the analysis of cell line secretomes."

[9].
"Biological indicators of prognosis in Ewing's sarcoma: an emerging role for lectin galactoside-binding soluble 3 binding protein (LGALS3BP)."

[10].
"Mac-2 binding protein and galectin-3 expression in mucinous tumours of the ovary: an annealing control primer system and immunohistochemical study."
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