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NCS1 (基因名), Neuronal calcium sensor 1 (蛋白名), ncs1_bovin.
产品名称:

Bovine NCS1/ Neuronal calcium sensor 1 Recombinant Protein
NCS-1

货号:

R13770b

商标:
EIAab®
监管等级:
别名:

Frequenin homolog, NCS-1, FREQ

序列号:
Q2V8Y7
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cardiovascular
Bovine NCS1 Protein
规格 & 价格: cart
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Bovine NCS1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts in a calcium-independent manner with PI4KB, but only if myristoylated. This binding competes with CALN2/CABP7 binding to PI4KB. Interacts with KCND2, ARF1, ARF3, ARF5 and ARF6 (By similarity). Interacts in a calcium-dependent manner with PICK1 (via AH domain) (By similarity). Interacts with IL1RAPL1.


功能:
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.


亚细胞位置:
Golgi apparatus Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cytoplasm Perinuclear region Cytoplasm Cell membrane Peripheral membrane protein Membrane Lipid-anchor Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.


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