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GAP43 (基因名), Neuromodulin (蛋白名), neum_human.
产品名称:

Human GAP43/ Neuromodulin Recombinant Protein
神经调制蛋白

货号:

R1327h

商标:
EIAab®
监管等级:
别名:

Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, pp46

序列号:
P17677
来源:
E.coli
种属:
Human
标签:
His
序列:
1-238aa
预估分子量:
26.18 kDa (monomer)
纯度:
Greater than 98% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human GAP43 Protein
规格 & 价格: cart
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Human GAP43 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 3q13.31 by HGNC 3q13.31 by Entrez Gene 3q13.31 by Ensembl
GAP43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.


功能:
This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.


亚细胞位置:
Cell membrane Peripheral membrane protein Cytoplasmic side Cell projection Growth cone membrane Peripheral membrane protein Cytoplasmic side Cell junction Synapse Cell projection Filopodium membrane Peripheral membrane protein Cytoplasmic surface of growth cone and synaptic plasma membranes.


该产品尚未在任何出版物中被引用。

[1].
"Structure of the human gene for the neural phosphoprotein B-50 (GAP-43)."

[2].
"Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human."

[3].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[4].
"Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43."

[5].
"Growth-associated protein 43 (GAP-43) and synaptophysin alterations in the dentate gyrus of patients with schizophrenia."

[6].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[7].
"Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs."

[8].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[9].
"GAP43 stimulates inositol trisphosphate-mediated calcium release in response to hypotonicity."

[10].
"Poly(A) tail length-dependent stabilization of GAP-43 mRNA by the RNA-binding protein HuD."
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