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TACR1 (基因名), Substance-P receptor (蛋白名), nk1r_human.
产品名称:

Human TACR1/ Substance-P receptor Recombinant Protein
p物质受体

货号:

R0392h

商标:
EIAab®
监管等级:
别名:

NK-1 receptor, Tachykinin receptor 1, NK-1R, SPR, NK1R, TAC1R

序列号:
P25103
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human TACR1 Protein
规格 & 价格: cart
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Human TACR1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2p12 by HGNC 2p12 by Entrez Gene 2p12 by Ensembl
TACR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with ARRB1.


功能:
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.


亚细胞位置:
Cell membrane Multi-pass membrane protein



[1].
"Candidate-gene approach in fibromyalgia syndrome: association analysis of the genes encoding substance P receptor, dopamine transporter and alpha1-antitrypsin."

[2].
"Association and linkage analysis of candidate genes GRP, GRPR, CRHR1, and TACR1 in panic disorder."

[3].
"Association of genetic variations in neurokinin-2 receptor with enhanced cough sensitivity to capsaicin in chronic cough."

[4].
"Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345."

[5].
"Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor."
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