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NOS2 (基因名), Nitric oxide synthase, inducible (蛋白名), nos2_pig.
产品名称:

Pig NOS2/ Nitric oxide synthase, inducible Recombinant Protein
诱导型一氧化氮合酶

货号:

R0837p

商标:
EIAab®
监管等级:
别名:

Inducible NO synthase, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Inducible NOS

序列号:
P79290
来源:
E.coli
种属:
Pig
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Pig NOS2 Protein
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Pig NOS2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer. Binds SLC9A3R1 (By similarity). Interacts with GAPDH. Interacts with S100A8 and S100A9 to form the iNOS-S100A8/9 transnitrosylase complex.


功能:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.


亚细胞位置:
N/A



[1].
Yun-Feng Ni, Jian-Ke Kuai, Zi-Fan Lu, Guo-Dong Yang, Hai-Yan Fu, Jian Wang, Feng Tian, Xiao-Long Yan, Ya-Chao Zhao, Yun-Jie Wang, and Tao Jiang,
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