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NCR3LG1 (基因名), Natural cytotoxicity triggering receptor 3 ligand 1 (蛋白名), nr3l1_human.
产品名称:

Human NCR3LG1/ Natural cytotoxicity triggering receptor 3 ligand 1 Recombinant Protein
B7同系物6

货号:

R5225h

商标:
EIAab®
监管等级:
别名:

B7 homolog 6, B7-H6, B7H6

序列号:
Q68D85
来源:
E.coli
种属:
Human
标签:
His
序列:
159-258aa
预估分子量:
11.0 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
  • Human NCR3LG1 Protein
  • Human NCR3LG1 Protein
  • Human NCR3LG1 Protein
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Human NCR3LG1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human NCR3LG1 Protein
The PCR product of human NCR3LG1 gene was determined by 1% Agarose stained with EB.
Human NCR3LG1 Protein
Recombinant human NCR3LG1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 11p15.1 by HGNC 11p15.1 by Entrez Gene 11p15.1 by Ensembl
NCR3LG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Monomer. Interacts specifically with NCR3, but not with other natural killer cell-activating receptors, including NCR1, NCR2 and KLRK1.


功能:
Triggers NCR3-dependent natural killer cell activation.


亚细胞位置:
Cell membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans."

[2].
"Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6."

[3].
"Characterization of B7H6, an endogenous ligand for the NK cell activating receptor NKp30, reveals the identity of two different soluble isoforms during normal human pregnancy."

[4].
"B7-H6 expression is induced by lipopolysaccharide and facilitates cancer invasion and metastasis in human gliomas."

[5].
"High expression of B7-H6 in human glioma tissues promotes tumor progression."

[6].
"Architecture of the human interactome defines protein communities and disease networks."

[7].
"Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis."

[8].
"Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production."

[9].
"Knockdown of B7-H6 inhibits tumor progression and enhances chemosensitivity in B-cell non-Hodgkin lymphoma."

[10].
"B7H6-derived peptides trigger TNF-α-dependent immunostimulatory activity of lymphocytic NK92-MI cells."
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