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OASL (基因名), 2'-5'-oligoadenylate synthase-like protein (蛋白名), oasl_human.
产品名称:

Human OASL/ 2'-5'-oligoadenylate synthase-like protein Recombinant Protein

货号:

R15895h

商标:
EIAab®
监管等级:
别名:

2'-5'-OAS-related protein, 59 kDa 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14, p59 OASL, 2'-5'-OAS-RP, TR-interacting protein 14, p59OASL, TRIP14

序列号:
Q15646
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human OASL Protein
规格 & 价格: cart
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Human OASL Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 12q24.31 by HGNC 12q24.31 by Entrez Gene 12q24.31 by Ensembl
OASL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.


功能:
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.


亚细胞位置:
Isoform p30 Cytoplasm


该产品尚未在任何出版物中被引用。

[1].
"2',5'-Oligoadenylate synthetase-like gene highly induced by hepatitis C virus infection in human liver is inhibitory to viral replication in vitro."

[2].
"Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1."

[3].
"The human 2',5'-oligoadenylate synthetase-like gene (OASL) encoding the interferon-induced 56-kDa protein maps to chromosome 12q24.2 in the proximity of the 2',5'-OAS locus."

[4].
"p59OASL, a 2'-5' oligoadenylate synthetase like protein: a novel human gene related to the 2'-5' oligoadenylate synthetase family."

[5].
"Identification of OASL d, a splice variant of human OASL, with antiviral activity."

[6].
"Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits."

[7].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[8].
"Dengue hemorrhagic fever is associated with polymorphisms in JAK1."

[9].
"Variability in the 2'-5'-oligoadenylate synthetase gene cluster is associated with human predisposition to tick-borne encephalitis virus-induced disease."

[10].
"[Interferon-inducible genes 2', 5'-ollgoadenylate synthetase-like and tetratricopeptide repeats 2 are correlated with clinical features of patients with systemic lupus erythematosus]."
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