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ODF2 (基因名), Outer dense fiber protein 2 (蛋白名), odfp2_human.
产品名称:

Human ODF2/ Outer dense fiber protein 2 Recombinant Protein

货号:

R12036h

商标:
EIAab®
监管等级:
别名:

Cenexin, Outer dense fiber of sperm tails protein 2

序列号:
Q5BJF6
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human ODF2 Protein
规格 & 价格: cart
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Human ODF2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 9q34.11 by HGNC 9q34.11 by Entrez Gene 9q34.11 by Ensembl
ODF2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Self-associates. Associates with microtubules and forms a fibrillar structure partially linked to the microtubule network. Interacts via its C-terminus with PLK1 (PubMed:16966375). Interacts with ODF1 (By similarity). Interacts with MARK4; the interaction is required for localization of ODF2 to centrioles (PubMed:23400999).


功能:
Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.


亚细胞位置:
Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Cell projection Cilium Cytoplasm Cytoskeleton Microtubule organizing center Centrosome Centriole Cytoplasm Cytoskeleton Spindle pole Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.


该产品尚未在任何出版物中被引用。

[1].
"The microtubule affinity regulating kinase MARK4 promotes axoneme extension during early ciliogenesis."

[2].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[3].
"Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes."

[4].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[5].
"Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa."

[6].
"Human outer dense fiber gene, ODF2, localizes to chromosome 9q34."

[7].
"Interactional cloning of the 84-kDa major outer dense fiber protein Odf84. Leucine zippers mediate associations of Odf84 and Odf27."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation."

[10].
"Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68."
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