首页 > 重组蛋白 > Human OLFM4 Recombinant Protein

OLFM4 (基因名), Olfactomedin-4 (蛋白名), olfm4_human.

产品名称:

Human OLFM4/ Olfactomedin-4 Recombinant Protein
Olfactomedin-4

货号:

R8723h

商标:

EIAab^®

监管等级:

RUO

别名:

Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein, hOLfD, hGC-1, UNQ362/PRO698, OLM4, GW112

序列号:

Q6UX06

来源:

E.coli

种属:

Human

标签:

His

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

Cancer

规格 & 价格:

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Human OLFM4 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

更多信息，请参阅手册，或联系我们的技术支持: tech@eiaab.com.

基因位点

Cytogenetic band: 13q14.3 by HGNC 13q14.3 by Entrez Gene 13q14.3 by Ensembl

OLFM4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Homomultimer; disulfide-linked. Interacts with NDUFA13. Interacts with cell surface lectins (locutions ricinus communis agglutinin I, concanavalin-A and wheat germ agglutinin) and cadherin.

功能:

May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.

亚细胞位置:

Secreted Extracellular space Mitochondrion Subcellular location is not clearly defined: has been shown to be secreted (PubMed:16566923), but also in the mitochondrion (PubMed:15059901 and PubMed:20724538), cytoplasm and plasma membrane (PubMed:20724538) and in the nucleus (PubMed:15059901).

数据库链接

UniGene:

Hs.508113

SMR:

Q6UX06

STRING:

9606.ENSP00000219022

KEGG:

hsa:10562

MIM:

614061

Pfam:

PF02191

Uniprot:

Q6UX06

相关产品

Mouse Olfm4 ELISA Kit

Mouse Olfm4 CLIA Kit

Mouse Olfm4 Protein

Mouse Olfm4 Polyclonal Antibody

Mouse Olfm4 Monoclonal Antibody

序列长度:

510

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

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350:

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500:

510:

YDLSVLQKPQ |

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"A genome-wide association meta-analysis identifies new childhood obesity loci."

(PMID: 22484627)

[2].

"Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis."

(PMID: 20724538)

[3].

"Serum olfactomedin 4 (GW112, hGC-1) in combination with Reg IV is a highly sensitive biomarker for gastric cancer patients."

(PMID: 19670418)

[4].

"Olfactomedin 4 promotes S-phase transition in proliferation of pancreatic cancer cells."

(PMID: 17270022)

[5].

"The glycoprotein hGC-1 binds to cadherin and lectins."

(PMID: 16566923)

[6].

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."

(PMID: 12975309)

[7].

"Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development."

(PMID: 11867215)

[8].

"The pregnancy hormone human chorionic gonadotropin differentially regulates plasmacytoid and myeloid blood dendritic cell subsets."

(PMID: 29488661)

[9].

"OLFM4, LY6D and S100A7 as potent markers for distant metastasis in estrogen receptor-positive breast carcinoma."

(PMID: 30137688)

[10].

"The clinical significance and biological function of olfactomedin 4 in triple negative breast cancer."

(PMID: 27939521)

[1].

人Olfactomedin-4(OLFM4)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人Olfactomedin-4(OLFM4)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人Olfactomedin-4(OLFM4)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人Olfactomedin-4(OLFM4)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人Olfactomedin-4(OLFM4)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人Olfactomedin-4(OLFM4)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人Olfactomedin-4(OLFM4)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人Olfactomedin-4(OLFM4)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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