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OLIG2 (基因名), Oligodendrocyte transcription factor 2 (蛋白名), olig2_human.
产品名称:

Human OLIG2/ Oligodendrocyte transcription factor 2 Recombinant Protein
少突胶质细胞转录因子2

货号:

R15290h

商标:
EIAab®
监管等级:
别名:

Class B basic helix-loop-helix protein 1, Class E basic helix-loop-helix protein 19, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17, bHLHb1, bHLHe19, Oligo2, BHLHB1, BHLHE19, PRKCBP2, RACK17

序列号:
Q13516
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human OLIG2 Protein
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Human OLIG2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 21q22.11 by HGNC 21q22.11 by Entrez Gene 21q22.11 by Ensembl
OLIG2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with NKX2-2.


功能:
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development.


亚细胞位置:
Nucleus Cytoplasm The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2.


该产品尚未在任何出版物中被引用。

[1].
"A genetic family-based association study of OLIG2 in obsessive-compulsive disorder."

[2].
"Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors."

[3].
"The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene."

[4].
"Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2."

[5].
"1p19q LOH patterns and expression of p53 and Olig2 in gliomas: relation with histological types and prognosis."

[6].
"Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease."

[7].
"Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury."

[8].
"Candidate genes for the progression of malignant gliomas identified by microarray analysis."

[9].
"Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia."

[10].
"Diversity of glial cell components in pilocytic astrocytoma."
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