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OMA1 (基因名), Metalloendopeptidase OMA1, mitochondrial (蛋白名), oma1_human.
产品名称:

Human OMA1/ Metalloendopeptidase OMA1, mitochondrial Recombinant Protein

货号:

R7661h

商标:
EIAab®
监管等级:
别名:

Metalloprotease-related protein 1, Overlapping with the m-AAA protease 1 homolog, MPRP-1, MPRP1

序列号:
Q96E52
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human OMA1 Protein
规格 & 价格: cart
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Human OMA1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p32.2-p32.1 by HGNC 1p32.2-p32.1 by Entrez Gene 1p32.2-p32.1 by Ensembl
OMA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.


亚细胞位置:
Mitochondrion inner membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Identification of a human cDNA sequence which encodes a novel membrane-associated protein containing a zinc metalloprotease motif."

[2].
"C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization."

[3].
"Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression."

[4].
"Inducible proteolytic inactivation of OPA1 mediated by the OMA1 protease in mammalian cells."

[5].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[6].
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences."

[7].
"Architecture of the human interactome defines protein communities and disease networks."

[8].
"Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress."

[9].
"The BioPlex Network: A Systematic Exploration of the Human Interactome."

[10].
"N-terminome analysis of the human mitochondrial proteome."
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