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OSM (基因名), Oncostatin-M (蛋白名), oncm_human.
产品名称:

Human OSM/ Oncostatin-M Recombinant Protein
制瘤素M

货号:

R0110h

商标:
EIAab®
监管等级:
别名:

OSM

序列号:
P13725
来源:
E.coli
种属:
Human
标签:
His
序列:
26-221aa
预估分子量:
21.56 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Immunology
Human OSM Protein
规格 & 价格: cart
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Human OSM Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 22q12.2 by HGNC 22q12.2 by Entrez Gene 22q12.2 by Ensembl
OSM Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation."

[2].
"Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells."

[3].
"Oncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6."

[4].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[5].
"The inflammatory mediator oncostatin M induces angiopoietin 2 expression in endothelial cells in vitro and in vivo."

[6].
"Gingival crevicular fluid levels of oncostatin M in periodontal conditions."

[7].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[8].
"Thrombin induces the expression of oncostatin M via AP-1 activation in human macrophages: a link between coagulation and inflammation."

[9].
"Oncostatin M as a target biological molecule of preeclampsia."

[10].
"Oncostatin M (OSM) is increased in asthma with incompletely reversible airflow obstruction."
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