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OSTN (基因名), Osteocrin (蛋白名), ostn_human.
产品名称:

Human OSTN/ Osteocrin Recombinant Protein

货号:

R16122h

商标:
EIAab®
监管等级:
别名:

Musclin

序列号:
P61366
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human OSTN Protein
规格 & 价格: cart
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Human OSTN Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 3q28 by HGNC 3q28 by Entrez Gene 3q28 by Ensembl
OSTN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with NPR3.


功能:
Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production.


亚细胞位置:
Secreted


该产品尚未在任何出版物中被引用。

[1].
"Characterization of osteocrin expression in human bone."

[2].
"Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype."

[3].
"Evolution of Osteocrin as an activity-regulated factor in the primate brain."

[4].
"High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men."

[5].
"Musclin, a novel skeletal muscle-derived secretory factor."

[6].
"Increased circulating levels of musclin in newly diagnosed type 2 diabetic patients."

[7].
"Musclin is an activity-stimulated myokine that enhances physical endurance."

[8].
"Osteocrin--beyond just another bone protein?"

[9].
"Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide."

[10].
"[Osteocrin is a new signaling molecule acting on bone]."
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