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HCRTR1 (基因名), Orexin receptor type 1 (蛋白名), ox1r_human.
产品名称:

Human HCRTR1/ Orexin receptor type 1 Recombinant Protein
食欲素受体

货号:

R0984h

商标:
EIAab®
监管等级:
别名:

Hypocretin receptor type 1, Ox-1-R

序列号:
O43613
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Metabolism
Human HCRTR1 Protein
规格 & 价格: cart
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Human HCRTR1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p35.2 by HGNC 1p35.2 by Entrez Gene 1p35.2 by Ensembl
HCRTR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).


亚细胞位置:
Cell membrane Multi-pass membrane protein


该产品尚未在任何出版物中被引用。

[1].
"The orexin 1 receptor (HCRTR1) gene as a susceptibility gene contributing to polydipsia-hyponatremia in schizophrenia."

[2].
"Association of an orexin 1 receptor 408Val variant with polydipsia-hyponatremia in schizophrenic subjects."

[3].
"A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains."

[4].
"Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior."

[5].
"Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors."

[6].
"Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients."

[7].
"Association study of 182 candidate genes in anorexia nervosa."

[8].
"A common variant in DRD3 receptor is associated with autism spectrum disorder."

[9].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[10].
"Short food deprivation inhibits orexin receptor 1 expression and orexin-A induced intracellular calcium signaling in acutely isolated duodenal enterocytes."
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