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P3H1 (基因名), Prolyl 3-hydroxylase 1 (蛋白名), p3h1_human.
产品名称:

Human P3H1/ Prolyl 3-hydroxylase 1 Recombinant Protein
脯氨酰3-羟化酶1

货号:

R15328h

商标:
EIAab®
监管等级:
别名:

Growth suppressor 1, Leucine- and proline-enriched proteoglycan 1, Leprecan-1, PSEC0109, GROS1, LEPRE1

序列号:
Q32P28
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human P3H1 Protein
规格 & 价格: cart
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Human P3H1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 1p34.2 by HGNC 1p34.2 by Entrez Gene 1p34.2 by Ensembl
P3H1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.


亚细胞位置:
Secreted Extracellular space Extracellular matrix Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG).


该产品尚未在任何出版物中被引用。

[1].
"Gros1, a potential growth suppressor on chromosome 1: its identity to basement membrane-associated proteoglycan, leprecan."

[2].
"Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation."

[3].
"Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta."

[4].
"Prolyl 3-hydroxylase 1 and CRTAP are mutually stabilizing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex."

[5].
"Null mutations in LEPRE1 and CRTAP cause severe recessive osteogenesis imperfecta."

[6].
"Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding."

[7].
"CRTAP and LEPRE1 mutations in recessive osteogenesis imperfecta."

[8].
"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."

[9].
"Complete sequencing and characterization of 21,243 full-length human cDNAs."

[10].
"Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes."
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