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F2R (基因名), Proteinase-activated receptor 1 (蛋白名), par1_human.
产品名称:

Human F2R/ Proteinase-activated receptor 1 Recombinant Protein
蛋白酶激活受体1

货号:

R0826h

商标:
EIAab®
监管等级:
别名:

Coagulation factor II receptor, Thrombin receptor, PAR-1, CF2R, PAR1, TR

序列号:
P25116
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human F2R Protein
规格 & 价格: cart
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Human F2R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 5q13.3 by HGNC 5q13.3 by Entrez Gene 5q13.3 by Ensembl
F2R Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.


亚细胞位置:
Cell membrane Multi-pass membrane protein



[1].
"Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin."

[2].
"The protease-activated receptor 1 possesses a functional and cleavable signal peptide which is necessary for receptor expression."

[3].
"New gene functions in megakaryopoiesis and platelet formation."

[4].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[5].
"Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth."

[6].
"Kallikrein-related peptidase 4: a new activator of the aberrantly expressed protease-activated receptor 1 in colon cancer cells."

[7].
"Kallikrein-related peptidase-4 initiates tumor-stroma interactions in prostate cancer through protease-activated receptor-1."

[8].
"Protease-activated receptor-1 (PAR-1) promotes the motility of human melanomas and is associated to their metastatic phenotype."

[9].
"N-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization."

[10].
"The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men."
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