首页 > 重组蛋白 > Human HSPG2 Recombinant Protein

HSPG2 (基因名), Basement membrane-specific heparan sulfate proteoglycan core protein (蛋白名), pgbm_human.

产品名称:

Human HSPG2/ Basement membrane-specific heparan sulfate proteoglycan core protein Recombinant Protein
硫酸乙酰肝素蛋白聚糖/串珠素

货号:

R0565h

商标:

EIAab^®

监管等级:

RUO

别名:

Perlecan, PLC, HSPG

序列号:

P98160

来源:

E.coli

种属:

Human

标签:

His

序列:

4120-4391aa

预估分子量:

29.92 kDa (monomer)

纯度:

Greater than 95% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human HSPG2 Protein

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产品说明书

说明书:

MSDS:

在线询价

数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

Recombinant human HSPG2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 1p36.12 by HGNC 1p36.12 by Entrez Gene 1p36.12 by Ensembl

HSPG2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Purified perlecan has a strong tendency to aggregate in dimers or stellate structures. It interacts with other basement membrane components such as laminin, prolargin and collagen type IV. Interacts with COL13A1, FGFBP1 and VWA1. Interacts (via C-terminus) with ECM1 (via C-terminus).

功能:

The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

亚细胞位置:

Secreted Extracellular space Extracellular matrix Basement membrane

数据库链接

UniGene:

Hs.562227

SMR:

P98160

STRING:

9606.ENSP00000363827

KEGG:

hsa:3339

MIM:

142461

Pfam:

PF00008

Uniprot:

P98160

相关产品

Mouse Hspg2 ELISA Kit

Mouse Hspg2 CLIA Kit

Mouse Hspg2 Protein

Mouse Hspg2 Polyclonal Antibody

Mouse Hspg2 Monoclonal Antibody

序列长度:

4391

序列:

仅供参考，详细请咨询（services@eiaab.com）

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GITGCVKNLV | LHSARPGAPP | PQPLDLQHRA | QAGANTRPCP | S

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"An association study of a polymorphism in the heparan sulfate proteoglycan gene (perlecan, HSPG2) and Alzheimer's disease."

(PMID: 15211644)

[2].

"Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1----p35 and identification of a BamHI restriction fragment length polymorphism."

(PMID: 1685141)

[3].

"No replication of genetic association between candidate polymorphisms and Alzheimer's disease."

(PMID: 19889475)

[4].

"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

(PMID: 20628086)

[5].

"A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM)."

(PMID: 20673868)

[6].

"Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes."

(PMID: 20452482)

[7].

"The intracranial aneurysm susceptibility genes HSPG2 and CSPG2 are not associated with abdominal aortic aneurysm."

(PMID: 20053631)

[8].

"Association of the HSPG2 gene with neuroleptic-induced tardive dyskinesia."

(PMID: 20072119)

[9].

"Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity."

(PMID: 19789387)

[10].

"Preliminary results in a study regarding the relationship between perlecan gene polymorphism and spinal muscular atrophy type I disease."

(PMID: 19839757)

[1].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人硫酸乙酰肝素蛋白聚糖/串珠素(HSPG2)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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