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PLEKHA8 (基因名), Pleckstrin homology domain-containing family A member 8 (蛋白名), pkha8_canfa.
产品名称:

Dog PLEKHA8/ Pleckstrin homology domain-containing family A member 8 Recombinant Protein

货号:

R3614d

商标:
EIAab®
监管等级:
别名:

Phosphatidylinositol-four-phosphate adapter protein 2, FAPP-2, PH domain-containing family A member 8, FAPP2

序列号:
D2KC46
来源:
E.coli
种属:
Dog
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Dog PLEKHA8 Protein
规格 & 价格: cart
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Dog PLEKHA8 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Homodimer. Interacts with ARF1; the interaction together with phosphatidylinositol 4-phosphate binding is required for FAPP2 GlcCer transfer ability.


功能:
Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.


亚细胞位置:
Cytoplasm Golgi apparatus Trans-Golgi network membrane Membrane Peripheral membrane protein Mainly localized to the trans-Golgi network (TGN) but also found at the rims of Golgi cisternae. Associates with ARF1 at Golgi apparatus membranes.


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