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ALPL (基因名), Alkaline phosphatase, tissue-nonspecific isozyme (蛋白名), ppbt_human.
产品名称:

Human ALPL/ Alkaline phosphatase, tissue-nonspecific isozyme Recombinant Protein
碱性磷酸酶,组织非特异性同工

货号:

R1091h

商标:
EIAab®
监管等级:
别名:

Alkaline phosphatase liver/bone/kidney isozyme, AP-TNAP, BALP

序列号:
P05186
来源:
E.coli
种属:
Human
标签:
His
序列:
80-205aa
预估分子量:
13.86 kDa (monomer)
纯度:
Greater than 95% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
  • Human ALPL Protein
  • Human ALPL Protein
  • Human ALPL Protein
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Human ALPL Protein
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产品说明书
数据表: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
The sequence analysis of human ALPL protein including hydrophilcity, hydrophobicity and antigenicity.
Human ALPL Protein
Recombinant human ALPL protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 1p36.12 by HGNC 1p36.12 by Entrez Gene 1p36.12 by Ensembl
ALPL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi).


亚细胞位置:
Cell membrane Lipid-anchor GPI-anchor


该产品尚未在任何出版物中被引用。

[1].
"Severe hypercalcaemia and respiratory insufficiency associated with infantile hypophosphatasia caused by two novel mutations of the tissue-nonspecific alkaline phosphatase gene."

[2].
"Association of ALPL and ENPP1 gene polymorphisms with bone strength related skeletal traits in a Chuvashian population."

[3].
"Mild forms of hypophosphatasia mostly result from dominant negative effect of severe alleles or from compound heterozygosity for severe and moderate alleles."

[4].
"Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations."

[5].
"Association of a TNAP haplotype with ankylosing spondylitis."

[6].
"Investigation of the role of ENPP1 and TNAP genes in chondrocalcinosis."

[7].
"Functional analysis of the single nucleotide polymorphism (787T>C) in the tissue-nonspecific alkaline phosphatase gene associated with BMD."

[8].
"Common mutations F310L and T1559del in the tissue-nonspecific alkaline phosphatase gene are related to distinct phenotypes in Japanese patients with hypophosphatasia."

[9].
"Denaturing gradient gel electrophoresis analysis of the tissue nonspecific alkaline phosphatase isoenzyme gene in hypophosphatasia."

[10].
"Twelve novel mutations in the tissue-nonspecific alkaline phosphatase gene (ALPL) in patients with various forms of hypophosphatasia."
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