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PGR (基因名), Progesterone receptor (蛋白名), prgr_canfa.
产品名称:

Dog PGR/ Progesterone receptor Recombinant Protein
孕酮受体

货号:

R1273d

商标:
EIAab®
监管等级:
别名:

Nuclear receptor subfamily 3 group C member 3, PR, NR3C3

序列号:
Q9GLW0
来源:
E.coli
种属:
Dog
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Dog PGR Protein
规格 & 价格: cart
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Dog PGR Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
Interacts with SMARD1 and UNC45A. Interacts with CUEDC2; the interaction promotes ubiquitination, decreases sumoylation, and repesses transcriptional activity. Interacts with PIAS3; the interaction promotes sumoylation of PR in a hormone-dependent manner, inhibits DNA-binding, and alters nuclear export. Interacts with SP1; the interaction requires ligand-induced phosphorylation on Ser-349 by ERK1/2-MAPK. Interacts with PRMT2.


功能:
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved in activation of c-SRC/MAPK signaling on hormone stimulation.


亚细胞位置:
Nucleus Cytoplasm Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.


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