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PRTN3 (基因名), Myeloblastin (蛋白名), prtn3_human.
产品名称:

Human PRTN3/ Myeloblastin Recombinant Protein
成髓细胞素

货号:

R8936h

商标:
EIAab®
监管等级:
别名:

AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen, PR-3, NP-4, MBN

序列号:
P24158
来源:
E.coli
种属:
Human
标签:
His
序列:
28-248aa
预估分子量:
24.31 kDa (monomer)
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human PRTN3 Protein
规格 & 价格: cart
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Human PRTN3 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 19p13.3 by HGNC 19p13.3 by Entrez Gene 19p13.3 by Ensembl
PRTN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.


亚细胞位置:
N/A


该产品尚未在任何出版物中被引用。

[1].
"Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils."

[2].
"Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing."

[3].
"Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism."

[4].
"Proteinase 3 gene polymorphisms and Wegener's granulomatosis."

[5].
"The crystal structure of PR3, a neutrophil serine proteinase antigen of Wegener's granulomatosis antibodies."

[6].
"Structure, chromosomal assignment, and expression of the gene for proteinase-3. The Wegener's granulomatosis autoantigen."

[7].
"Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter."

[8].
"Wegener autoantigen and myeloblastin are encoded by a single mRNA."

[9].
"Characterization of proteinase-3 (PR-3), a neutrophil serine proteinase. Structural and functional properties."

[10].
"Anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis recognize an elastinolytic enzyme."
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