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RAB7B (基因名), Ras-related protein Rab-7b (蛋白名), rab7b_bovin.
产品名称:

Bovine RAB7B/ Ras-related protein Rab-7b Recombinant Protein
Ras-related蛋白质Rab-7b

货号:

R7754b

商标:
EIAab®
监管等级:
序列号:
Q08DE8
来源:
E.coli
种属:
Bovine
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Bovine RAB7B Protein
规格 & 价格: cart
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Bovine RAB7B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
通用注释


亚单元:
N/A


功能:
Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.


亚细胞位置:
Late endosome Lysosome Golgi apparatus Golgi apparatus Trans-Golgi network Cytoplasmic vesicle Phagosome Cytoplasmic vesicle Phagosome membrane Lipid-anchor Cytoplasmic side Recruited to phagosomes containing S.aureus or M.tuberculosis.


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