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SLC40A1 (基因名), Solute carrier family 40 member 1 (蛋白名), s40a1_human.
产品名称:

Human SLC40A1/ Solute carrier family 40 member 1 Recombinant Protein
溶质运载蛋白家族40成员1

货号:

R1631h

商标:
EIAab®
监管等级:
别名:

Ferroportin-1, Iron-regulated transporter 1, MSTP079, FPN1, IREG1, SLC11A3

序列号:
Q9NP59
来源:
E.coli
种属:
Human
标签:
His
序列:
1-180aa
预估分子量:
19.8 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human SLC40A1 Protein
规格 & 价格: cart
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Human SLC40A1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2q32.2 by HGNC 2q32.2 by Entrez Gene 2q32.2 by Ensembl
SLC40A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Identified in a complex with STOM.


功能:
May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).


亚细胞位置:
Cell membrane Multi-pass membrane protein Localized to the basolateral membrane of polarized epithelial cells.


该产品尚未在任何出版物中被引用。

[1].
"Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene."

[2].
"Does the SLC40A1 gene modify HFE-related haemochromatosis phenotypes?"

[3].
"DNA-array of gene variants in venous leg ulcers: detection of prognostic indicators."

[4].
"H63D homozygotes with hyperferritinaemia: Is this genotype, the primary cause of iron overload?"

[5].
"Genetic and clinical heterogeneity of ferroportin disease."

[6].
"Investigation of genetic variants of genes of the hemochromatosis pathway and their role in breast cancer."

[7].
"The ferroportin disease."

[8].
"Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload."

[9].
"Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutations."

[10].
"Autosomal dominant reticuloendothelial iron overload (HFE type 4) due to a new missense mutation in the FERROPORTIN 1 gene (SLC11A3) in a large French-Canadian family."
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