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SFRP4 (基因名), Secreted frizzled-related protein 4 (蛋白名), sfrp4_human.
产品名称:

Human SFRP4/ Secreted frizzled-related protein 4 Recombinant Protein
分泌性卷曲相关蛋白4

货号:

R1650h

商标:
EIAab®
监管等级:
别名:

Frizzled protein, human endometrium, FrpHE, sFRP-4, FRPHE

序列号:
Q6FHJ7
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human SFRP4 Protein
规格 & 价格: cart
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Human SFRP4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 7p14.1 by HGNC 7p14.1 by Entrez Gene 7p14.1 by Ensembl
SFRP4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
N/A


功能:
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (By similarity). SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927).


亚细胞位置:
Secreted Cytoplasmic in ovarian tumor cells.


该产品尚未在任何出版物中被引用。

[1].
"Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy."

[2].
"Expression of secreted frizzled-related protein 4 (SFRP4) in primary serous ovarian tumours."

[3].
"Wnt antagonist gene polymorphisms and renal cancer."

[4].
"Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent."

[5].
"Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease."

[6].
"Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer."

[7].
"Association between polymorphisms in Wnt signaling pathway genes and bone mineral density in postmenopausal Korean women."

[8].
"Increased expression of secreted frizzled-related protein 4 in polycystic kidneys."

[9].
"Expression of secreted frizzled-related protein 4 in the primate placenta."

[10].
"A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits."
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