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SGPL1 (基因名), Sphingosine-1-phosphate lyase 1 (蛋白名), sgpl1_human.
产品名称:

Human SGPL1/ Sphingosine-1-phosphate lyase 1 Recombinant Protein
Sphingosine-1-phosphate裂合酶1

货号:

R15015h

商标:
EIAab®
监管等级:
别名:

Sphingosine-1-phosphate aldolase, S1PL, KIAA1252

序列号:
O95470
来源:
E.coli
种属:
Human
标签:
His
序列:
Recombinant protein
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Signal Transduction
Human SGPL1 Protein
规格 & 价格: cart
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Human SGPL1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 10q22.1 by HGNC 10q22.1 by Entrez Gene 10q22.1 by Ensembl
SGPL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer.


功能:
Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.


亚细胞位置:
Endoplasmic reticulum membrane Single-pass type III membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer."

[2].
"Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry."

[3].
"Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency."

[4].
"Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome."

[5].
"Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications."
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