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STAB1 (基因名), Stabilin-1 (蛋白名), stab1_human.
产品名称:

Human STAB1/ Stabilin-1 Recombinant Protein
Stabilin-1

货号:

R1417h

商标:
EIAab®
监管等级:
别名:

Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, MS-1 antigen, FEEL-1, FEEL1, KIAA0246

序列号:
Q9NY15
来源:
E.coli
种属:
Human
标签:
His
序列:
91-230aa
预估分子量:
15.4 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human STAB1 Protein
规格 & 价格: cart
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Human STAB1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human STAB1 Protein
Recombinant human STAB1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 3p21.1 by HGNC 3p21.1 by Entrez Gene 3p21.1 by Ensembl
STAB1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with CHID1.


功能:
Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.


亚细胞位置:
Membrane Single-pass type I membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues."

[2].
"Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway."

[3].
"FEEL-1, a novel scavenger receptor with in vitro bacteria-binding and angiogenesis-modulating activities."

[4].
"Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population."

[5].
"Cross-talk between endocytic clearance and secretion in macrophages."

[6].
"A novel GGA-binding site is required for intracellular sorting mediated by stabilin-1."

[7].
"Alternatively activated macrophages regulate extracellular levels of the hormone placental lactogen via receptor-mediated uptake and transcytosis."

[8].
"Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC."

[9].
"Human hepatic sinusoidal endothelial cells can be distinguished by expression of phenotypic markers related to their specialised functions in vivo."

[10].
"CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium."
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