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SYN1 (基因名), Synapsin-1 (蛋白名), syn1_human.
产品名称:

Human SYN1/ Synapsin-1 Recombinant Protein
类的突触蛋白I

货号:

R1690h

商标:
EIAab®
监管等级:
别名:

Brain protein 4.1, Synapsin I

序列号:
P17600
来源:
E.coli
种属:
Human
标签:
His
序列:
113-420aa
预估分子量:
33.88 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human SYN1 Protein
规格 & 价格: cart
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Human SYN1 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xp11.3-p11.23 by HGNC Xp11.3-p11.23 by Entrez Gene Xp11.3-p11.23 by Ensembl
SYN1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Homodimer. Interacts with CAPON. Forms a ternary complex with NOS1. Isoform Ib interacts with PRNP.


功能:
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level.


亚细胞位置:
Cell junction Synapse Golgi apparatus


该产品尚未在任何出版物中被引用。

[1].
"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

[2].
"Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment."

[3].
"The DNA sequence of the human X chromosome."

[4].
"Phosphoproteomic analysis of synaptosomes from human cerebral cortex."

[5].
"Identification of a mutation in synapsin I, a synaptic vesicle protein, in a family with epilepsy."

[6].
"The structure of the human synapsin I gene and protein."

[7].
"The 5'-flanking region of the synapsin I gene. A G+C-rich, TATA- and CAAT-less, phylogenetically conserved sequence with cell type-specific promoter function."

[8].
"Architecture of the human interactome defines protein communities and disease networks."

[9].
"A novel SYN1 missense mutation in non-syndromic X-linked intellectual disability affects synaptic vesicle life cycle, clustering and mobility."

[10].
"DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression."
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