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SYNPO (基因名), Synaptopodin (蛋白名), synpo_human.
产品名称:

Human SYNPO/ Synaptopodin Recombinant Protein
突触极蛋白

货号:

R1122h

商标:
EIAab®
监管等级:
别名:

KIAA1029

序列号:
Q8N3V7
来源:
E.coli
种属:
Human
标签:
His
序列:
501-650aa
预估分子量:
16.5 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Neurosciences
Human SYNPO Protein
规格 & 价格: cart
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Human SYNPO Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human SYNPO Protein
Recombinant human SYNPO protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 5q33.1 by HGNC 5q33.1 by Entrez Gene 5q33.1 by Ensembl
SYNPO Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with BAIAP1. Interacts with actin (By similarity). Interacts (via PPxY motifs) with WWC1 (via WW domains).


功能:
Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.


亚细胞位置:
Cytoplasm Cytoskeleton Cell junction Tight junction Perikaryon Cell projection Dendritic spine Cell junction Synapse Postsynaptic cell membrane Postsynaptic density Cell junction Synapse Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.


该产品尚未在任何出版物中被引用。

[1].
"Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes."

[2].
"Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."

[3].
"Human variation in alcohol response is influenced by variation in neuronal signaling genes."

[4].
"Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis."

[5].
"KIBRA modulates directional migration of podocytes."

[6].
"Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia."

[7].
"Synaptopodin orchestrates actin organization and cell motility via regulation of RhoA signalling."

[8].
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

[9].
"Expression of synaptopodin and GLEPP1 as markers of steroid responsiveness in primary focal segmental glomerulosclerosis."

[10].
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
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