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TAF1B (基因名), TATA box-binding protein-associated factor RNA polymerase I subunit B (蛋白名), taf1b_human.
产品名称:

Human TAF1B/ TATA box-binding protein-associated factor RNA polymerase I subunit B Recombinant Protein

货号:

R3422h

商标:
EIAab®
监管等级:
别名:

RNA polymerase I-specific TBP-associated factor 63 kDa, TATA box-binding protein-associated factor 1B, Transcription initiation factor SL1/TIF-IB subunit B, TAFI63, TBP-associated factor 1B

序列号:
Q53T94
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human TAF1B Protein
规格 & 价格: cart
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Human TAF1B Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 2p25.1 by HGNC 2p25.1 by Entrez Gene 2p25.1 by Ensembl
TAF1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Interacts with FLNA (via N-terminus) (By similarity). Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. In the complex interacts directly with TBP, TAF1A and TAF1C. Interaction of the SL1/TIF-IB subunits with TBP excludes interaction of TBP with the transcription factor IID (TFIID) subunits. Interacts with TBP and RRN3.


功能:
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3.


亚细胞位置:
Nucleus Nucleolus


该产品尚未在任何出版物中被引用。

[1].
"Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1."

[2].
"Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits."

[3].
"Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors."

[4].
"TAF1B is a TFIIB-like component of the basal transcription machinery for RNA polymerase I."

[5].
"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score."

[6].
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."

[7].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[8].
"Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability."

[9].
"hRRN3 is essential in the SL1-mediated recruitment of RNA Polymerase I to rRNA gene promoters."

[10].
"Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells."
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