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TAF4 (基因名), Transcription initiation factor TFIID subunit 4 (蛋白名), taf4_human.
产品名称:

Human TAF4/ Transcription initiation factor TFIID subunit 4 Recombinant Protein

货号:

R9669h

商标:
EIAab®
监管等级:
别名:

RNA polymerase II TBP-associated factor subunit C, TBP-associated factor 4, Transcription initiation factor TFIID 130 kDa subunit, Transcription initiation factor TFIID 135 kDa subunit, TAF(II)130, TAF(II)135, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135

序列号:
O00268
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human TAF4 Protein
规格 & 价格: cart
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Human TAF4 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 20q13.33 by HGNC 20q13.33 by Entrez Gene 20q13.33 by Ensembl
TAF4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Component of the TFTC-HAT complex, at least composed of TAF5L, TAF6L, TADA3L, SUPT3H, TAF2, TAF4, TAF5, GCN5L2/GCN5, TAF10 and TRRAP. Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Interacts with ATF7; the interaction inhibits ATF7-mediated tranactivation. Interacts with SV40 Large T antigen.


功能:
Part of the TFIID complex, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Potentiates transcriptional activation by the AF-2S of the retinoic acid, vitamin D3 and thyroid hormone.


亚细胞位置:
Nucleus


该产品尚未在任何出版物中被引用。

[1].
"The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs."

[2].
"Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells."

[3].
"Molecular cloning and analysis of two subunits of the human TFIID complex: hTAFII130 and hTAFII100."

[4].
"Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals."

[5].
"Association of genetic variants with hemorrhagic stroke in Japanese individuals."
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