EIAab
首页  >  重组蛋白  >  Human TAF4B Recombinant Protein
TAF4B (基因名), Transcription initiation factor TFIID subunit 4B (蛋白名), taf4b_human.
产品名称:

Human TAF4B/ Transcription initiation factor TFIID subunit 4B Recombinant Protein

货号:

R3424h

商标:
EIAab®
监管等级:
别名:

Transcription initiation factor TFIID 105 kDa subunit, TAF(II)105, TAF2C2, TAFII105

序列号:
Q92750
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human TAF4B Protein
规格 & 价格: cart
×
Human TAF4B Protein
邮箱 *
消息 *
Please 登录.
产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: 18q11.1 by HGNC 18q11.1 by Entrez Gene 18q11.1 by Ensembl
TAF4B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Heterodimerizes with TAF12/TFII20 via the C-terminal H2A-like histone-fold domain. This heterodimer forms a histone-like octamer with the TAF6/TAFII70-TAF9/TAFII31 heterodimer. Interacts with P65/RELA homodimers and P65/RELA-REL heterodimers. Interaction with POU2AF1, via its C-terminal activation domain, is required for octamer-dependent transcription.


功能:
Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis.


亚细胞位置:
Nucleus Cytoplasm Export into the cytoplasm is mediated by a CRM1-independent nuclear export pathway and not by phosphorylation.


该产品尚未在任何出版物中被引用。

[1].
"Cyclic AMP-dependent modification of gonad-selective TAF(II)105 in a human ovarian granulosa cell line."

[2].
"A composite nuclear export signal in the TBP-associated factor TAFII105."

[3].
"Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes."

[4].
"Specific interaction of TAFII105 with OCA-B is involved in activation of octamer-dependent transcription."

[5].
"Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130."

[6].
"Truncating mutations in TAF4B and ZMYND15 causing recessive azoospermia."

[7].
"TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes."

[8].
"Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene."

[9].
"Core promoter binding by histone-like TAF complexes."

[10].
"Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics."
关闭
Sample Data
关闭
Sample Data
关闭
Sample Data
用户中心 close
购物车 close
我的收藏 close
我的足迹 close
清除
产品对比 close
用户中心
购物车
我的收藏
我的足迹
产品对比
回到顶部
通知
new 咨询
规格 数量 单价 (¥) 小计 1 (¥)
小计 2:
triangle
规格 数量 单价 (¥)
你想做我们的代理并得到更低的折扣吗?
请联系我们:
电话:027-59234612(+86)
传真:027-59234610(+86)
邮箱:sales@eiaab.com