首页 > 重组蛋白 > Human TCP1 Recombinant Protein

TCP1 (基因名), T-complex protein 1 subunit alpha (蛋白名), tcpa_human.

产品名称:

Human TCP1/ T-complex protein 1 subunit alpha Recombinant Protein

货号:

R16168h

商标:

EIAab^®

监管等级:

RUO

别名:

CCT-alpha, TCP-1-alpha, CCT1, CCTA

序列号:

P17987

来源:

E.coli

种属:

Human

标签:

His

序列:

1-556aa

预估分子量:

61.16 kDa (monomer)

纯度:

>90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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产品说明书

说明书:

MSDS:

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数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

Recombinant human TCP1 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 6q25.3 by HGNC 6q25.3 by Entrez Gene 6q25.3 by Ensembl

TCP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8.

功能:

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

亚细胞位置:

Cytoplasm Cytoplasm Cytoskeleton Microtubule organizing center Centrosome

数据库链接

UniGene:

Hs.363137

SMR:

P17987

STRING:

9606.ENSP00000317334

KEGG:

hsa:6950

MIM:

186980

Pfam:

PF00118

Uniprot:

P17987

相关产品

Mouse Tcp1 ELISA Kit

Rat Tcp1 ELISA Kit

Bovine TCP1 ELISA Kit

Mouse Tcp1 CLIA Kit

Rat Tcp1 CLIA Kit

序列长度:

556

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

556:

SGALND

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol."

(PMID: 1630492)

[2].

"The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region."

(PMID: 3653076)

[3].

"Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1."

(PMID: 25467444)

[4].

"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

(PMID: 20628086)

[5].

"BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly."

(PMID: 20080638)

[6].

"Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl."

(PMID: 21098288)

[7].

"A genome-wide association study identifies novel and functionally related susceptibility Loci for Kawasaki disease."

(PMID: 19132087)

[8].

"Family-based association studies of the TCP1 gene and schizophrenia in the Chinese Han population."

(PMID: 16465465)

[9].

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."

(PMID: 17081983)

[10].

"Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding."

(PMID: 15745879)

[1].

人TCP1重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人TCP1重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人TCP1重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人TCP1重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人TCP1重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人TCP1重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人TCP1重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人TCP1重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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