首页 > 重组蛋白 > Human TEAD2 Recombinant Protein

TEAD2 (基因名), Transcriptional enhancer factor TEF-4 (蛋白名), tead2_human.

产品名称:

Human TEAD2/ Transcriptional enhancer factor TEF-4 Recombinant Protein
转录增强因子TEF-4

货号:

R3435h

商标:

EIAab^®

监管等级:

RUO

别名:

TEA domain family member 2, TEAD-2, TEF4

序列号:

Q15562

来源:

E.coli

种属:

Human

标签:

His

序列:

155-292aa

预估分子量:

15.18 kDa (monomer)

纯度:

Greater than 90% by SDS-PAGE

浓度:

Reconstitution Dependent

形态:

Liquid

内毒素水平:

Please contact protein@eiaab.com The technician for more information.

应用:

存储缓冲液:

50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)

存储:

Store at -20°C. (Avoid repeated freezing and thawing.)

研究领域:

规格 & 价格:

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Human TEAD2 Protein

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产品说明书

说明书:

MSDS:

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数据
文献
出版物
序列 / 3D
常见问题解答
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R&D 技术数据

Recombinant human TEAD2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.

基因位点

Cytogenetic band: 19q13.3 by HGNC 19q13.3 by Entrez Gene 19q13.3 by Ensembl

TEAD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)

通用注释

亚单元:

Interacts with YAP1 and WWTR1/TAZ.

功能:

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.

亚细胞位置:

Nucleus

数据库链接

UniGene:

Hs.515534

SMR:

Q15562

STRING:

9606.ENSP00000310701

KEGG:

hsa:8463

MIM:

601729

Pfam:

PF01285

Uniprot:

Q15562

相关产品

Mouse Tead2 ELISA Kit

Mouse Tead2 CLIA Kit

Mouse Tead2 Protein

Mouse Tead2 Polyclonal Antibody

Mouse Tead2 Monoclonal Antibody

序列长度:

447

序列:

仅供参考，详细请咨询（services@eiaab.com）

50:

100:

150:

200:

250:

300:

350:

400:

447:

SVLENFTILQ | VVTNRDTQEL | LLCTAYVFEV | STSERGAQHH | IYRLVRD

3D 模型:

3D 结构:

免疫原序列:

验证序列:

该产品尚未在任何出版物中被引用。

[1].

"Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis."

(PMID: 9889009)

[2].

"A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain."

(PMID: 8702974)

[3].

"Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study."

(PMID: 20628086)

[4].

"TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition."

(PMID: 19324877)

[5].

"TEAD mediates YAP-dependent gene induction and growth control."

(PMID: 18579750)

[6].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."

(PMID: 14702039)

[7].

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

(PMID: 15489334)

[8].

"Architecture of the human interactome defines protein communities and disease networks."

(PMID: 28514442)

[9].

"OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc."

(PMID: 28628118)

[10].

"Enabling systematic interrogation of protein-protein interactions in live cells with a versatile ultra-high-throughput biosensor platform."

(PMID: 26578655)

[1].

人转录增强因子TEF-4(TEAD2)重组蛋白是否是无菌的？

蛋白试剂瓶和蛋白保存液是经过高压灭菌的，但也不能保证蛋白是完全无菌的。如果要求蛋白是无菌的，可以用0.2微米的滤器对蛋白进行过滤。

[2].

人转录增强因子TEF-4(TEAD2)重组蛋白的保存缓冲液是什么？

纯化后的蛋白保存在PBS（58mM Na2HPO4, 17mM NaH2PO4, 68mM NaCl, pH7.4）里，并往里面加入500mM咪唑和10%甘油。

[3].

怎样确定人转录增强因子TEF-4(TEAD2)重组蛋白的浓度？

蛋白浓度的确定没有一个统一的标准，这主要取决于蛋白的氨基酸序列。伊艾博是根据不同测试的组合来测定蛋白浓度。考马斯亮蓝法、BCA法、氨基酸序列和氨基酸全序列分析法等都用来测定蛋白浓度。

[4].

人转录增强因子TEF-4(TEAD2)重组蛋白蛋白保存条件是怎样的？

蛋白应保存在 -20℃或 -80℃条件下，为了避免反复冻融，可以将蛋白分装成小份保存。

[5].

人转录增强因子TEF-4(TEAD2)重组蛋白是否可以用于活体实验？

重组蛋白没有用于任何的活体实验，因此蛋白的活性和半衰期是不确定的。

[6].

人转录增强因子TEF-4(TEAD2)重组蛋白的保质期是多久？

在适当的保存条件下，从购买之日起蛋白可以稳定保存6-12个月。适当的保存条件是:蛋白保存在-20°C o或 -80℃，保证蛋白的保存浓度高于0.1mg/ml，限制蛋白反复冻融的次数。我们公司常规的质量检测保证所有产品在销售时都有可接受的生物活性。但是我们不能控制终端用户蛋白的保存条件。如果产品在有效期内出现问题，请联系我们的技术支持。

[7].

你们蛋白和抗体的报价是怎么样的？

我们将根据你需要的蛋白和抗体的大小进行报价。

[8].

人转录增强因子TEF-4(TEAD2)重组蛋白是否能够提供蛋白片段？

我们现有的人的蛋白的序列可以有很多。你可以选择你感兴趣的靶向部分，我们将会按您的需求提供蛋白和抗体。

[9].

人转录增强因子TEF-4(TEAD2)重组蛋白的货期或发货时间一般是多长？

具体指标的货期需要确定。最快一周，最长可能一个月。

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