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F2 (基因名), Prothrombin (蛋白名), thrb_human.
产品名称:

Human F2/ Prothrombin Recombinant Protein
凝血原

货号:

R0710h

商标:
EIAab®
监管等级:
别名:

Coagulation factor II

序列号:
P00734
来源:
E.coli
种属:
Human
标签:
His
序列:
273-622aa
预估分子量:
38.5 kDa (monomer)
纯度:
Greater than 90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
Cancer
Human F2 Protein
规格 & 价格: cart
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Human F2 Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
在线询价


R&D 技术数据
Human F2 Protein
Recombinant human F2 protein was determined by 12% SDS-PAGE stained with Coomassie Blue under reducing conditions.
基因位点
Cytogenetic band: 11p11.2 by HGNC 11p11.2 by Entrez Gene 11p11.2 by Ensembl
F2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Heterodimer (named alpha-thrombin) of a light and a heavy chain; disulfide-linked. Forms a heterodimer with SERPINA5.


功能:
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.


亚细胞位置:
Secreted Extracellular space



[1].
"Impact of genetic polymorphisms on platelet function and aspirin resistance."

[2].
"Risk factors for failure of heparin thromboprophylaxis in patients with acute traumatic spinal cord injury."

[3].
"Causal relationship of susceptibility genes to ischemic stroke: comparison to ischemic heart disease and biochemical determinants."

[4].
"Thrombophilic risk factors in patients with cranial and spinal dural arteriovenous fistulae."

[5].
"Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls."

[6].
"Elevated prothrombin is a risk factor for cerebral arterial ischemia in young adults."

[7].
"G20210A prothrombin gene polymorphism and prothrombin activity in subjects with or without angiographically documented coronary artery disease."

[8].
"Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester."

[9].
"Combined factor V Leiden and prothrombin genotyping in patients presenting with thromboembolic episodes."

[10].
"Abdominal venous thrombosis in neonates and infants: role of prothrombotic risk factors - a multicentre case-control study. For the Childhood Thrombophilia Study Group."
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