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EDA2R (基因名), Tumor necrosis factor receptor superfamily member 27 (蛋白名), tnr27_human.
产品名称:

Human EDA2R/ Tumor necrosis factor receptor superfamily member 27 Recombinant Protein

货号:

R10631h

商标:
EIAab®
监管等级:
别名:

X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, UNQ2448/PRO5727/PRO34080, TNFRSF27, XEDAR

序列号:
Q9HAV5
来源:
E.coli
种属:
Human
标签:
His
纯度:
>90% by SDS-PAGE
浓度:
Reconstitution Dependent
形态:
Liquid
内毒素水平:
Please contact protein@eiaab.com The technician for more information.
应用:
存储缓冲液:
50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10%glycerol(PH8.0)
存储:
Store at -20°C. (Avoid repeated freezing and thawing.)
研究领域:
-
Human EDA2R Protein
规格 & 价格: cart
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Human EDA2R Protein
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产品说明书
说明书: 下载说明书
MSDS: MSDS
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R&D 技术数据
更多信息,请参阅手册,或联系我们的技术支持: tech@eiaab.com.
基因位点
Cytogenetic band: Xq12 by HGNC Xq12 by Entrez Gene Xq12 by Ensembl
EDA2R Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
基因位点
通用注释


亚单元:
Associates with TRAF1, TRAF3 and TRAF6.


功能:
Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.


亚细胞位置:
Membrane Single-pass type III membrane protein


该产品尚未在任何出版物中被引用。

[1].
"Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors."

[2].
"Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor."

[3].
"Susceptibility variants on chromosome 7p21.1 suggest HDAC9 as a new candidate gene for male-pattern baldness."

[4].
"XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway."

[5].
"FGFR2 is associated with hair thickness in Asian populations."

[6].
"Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness."

[7].
"EDA2R is associated with androgenetic alopecia."

[8].
"Repertoire of mouse ectodysplasin-A (EDA-A) isoforms."

[9].
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."

[10].
"Induction of apoptosis by X-linked ectodermal dysplasia receptor via a caspase 8-dependent mechanism."
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